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N Chiba Selected Research

Therapeutics

8/2012Optimization of cell-wall skeleton derived from Mycobacterium bovis BCG Tokyo 172 (SMP-105) emulsion in delayed-type hypersensitivity and antitumor models.
7/2011Breast tumor progression induced by loss of BTG2 expression is inhibited by targeted therapy with the ErbB/HER inhibitor lapatinib.
12/2009Phase I/II study of sequential therapy with irinotecan and S-1 for metastatic colorectal cancer.
6/2008Injection of cell-wall skeleton of Mycobacterium bovis BCG draining to a sentinel lymph node eliminates both lymph node metastases and the primary transplanted tumor.
3/2006The prevalence of Barrett's oesophagus in a cohort of 1040 Canadian primary care patients with uninvestigated dyspepsia undergoing prompt endoscopy.
5/2005Heartburn-dominant, uninvestigated dyspepsia: a comparison of 'PPI-start' and 'H2-RA-start' management strategies in primary care--the CADET-HR Study.
2/2004Economic evaluation of Helicobacter pylori eradication in the CADET-Hp randomized controlled trial of H. pylori-positive primary care patients with uninvestigated dyspepsia.
6/2003The prevalence of clinically significant endoscopic findings in primary care patients with uninvestigated dyspepsia: the Canadian Adult Dyspepsia Empiric Treatment - Prompt Endoscopy (CADET-PE) study.
6/2001Ranitidine bismuth citrate.
6/2000An evidence-based approach to the management of uninvestigated dyspepsia in the era of Helicobacter pylori. Canadian Dyspepsia Working Group.

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N Chiba Research Topics

Disease

5Infections
04/2014 - 02/2000
5Dyspepsia (Indigestion)
03/2006 - 06/2000
4Neoplasms (Cancer)
08/2012 - 01/2007
3Heartburn (Pyrosis)
02/2006 - 06/2000
3Gastroesophageal Reflux (GERD)
02/2006 - 06/2000
2Glaucoma
03/2006 - 08/2003
2Atrial Fibrillation
01/2001 - 07/2000
1Liver Failure
04/2015
1Mycoses (Diseases, Fungus)
04/2015
1Fibrosis (Cirrhosis)
04/2015
1Hypersensitivity (Allergy)
08/2012
1Edema (Dropsy)
08/2012
1Tuberculosis (Tuberculoses)
05/2012
1Carcinogenesis
07/2011
1Neoplasm Metastasis (Metastasis)
07/2011
1Breast Neoplasms (Breast Cancer)
07/2011
1Mitral Valve Insufficiency (Mitral Regurgitation)
02/2011
1Alveolar Bone Loss
02/2010
1Periodontitis
02/2010
1Pneumococcal Infections
01/2010
1Colorectal Neoplasms (Colorectal Cancer)
12/2009
1Lymphatic Metastasis
06/2008
1Ocular Hypertension (Glaucoma, Suspect)
03/2006
1Open-Angle Glaucoma (Glaucoma, Open Angle)
03/2006
1Uveitis
08/2003
1Stomach Ulcer (Gastric Ulcer)
06/2001
1Duodenal Ulcer (Curling's Ulcer)
01/2001
1Ulcer
01/2001
1Chromosome Inversion (Chromosomal Inversion)
07/2000
1Coinfection
03/2000

Drug/Important Bio-Agent (IBA)

3AcidsIBA
06/2003 - 06/2000
2Anti-Bacterial Agents (Antibiotics)IBA
04/2014 - 06/2001
2Cell Wall SkeletonIBA
08/2012 - 06/2008
2Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
03/2006 - 06/2000
2Latanoprost (Xalatan)FDA Link
03/2006 - 08/2003
2Pharmaceutical PreparationsIBA
03/2006 - 06/2001
2Ophthalmic Solutions (Eye Drops)IBA
03/2006 - 08/2003
2Esomeprazole (Nexium)FDA Link
02/2006 - 11/2004
2Omeprazole (Prilosec)FDA LinkGeneric
05/2005 - 02/2004
1Antifungal AgentsIBA
04/2015
1VaccinesIBA
04/2014
1MacrolidesIBA
04/2014
1EmulsionsIBA
08/2012
1ErbB Receptors (EGF Receptor)IBA
07/2011
1Lapatinib (GW572016)FDA Link
07/2011
1Tyrosine Kinase InhibitorsIBA
07/2011
1Adenosine Triphosphate (ATP)IBA
02/2011
1Nicorandil (SG 75)IBA
02/2011
1Potassium Channels (Potassium Channel)IBA
02/2011
1NitratesIBA
02/2011
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2010
1Messenger RNA (mRNA)IBA
02/2010
1Heptavalent Pneumococcal Conjugate Vaccine (Prevnar)IBA
01/2010
1Irinotecan (Camptosar)FDA LinkGeneric
12/2009
1ProdrugsIBA
12/2009
1Fluorouracil (Carac)FDA LinkGeneric
12/2009
1Neoplasm Antigens (Tumor Antigens)IBA
06/2008
1Paclitaxel (Taxol)FDA LinkGeneric
01/2007
1Interleukin-2 (IL2)IBA
01/2007
1Interleukin-2 Receptors (IL 2 Receptor)IBA
01/2007
1Cyclosporine (Ciclosporin)FDA LinkGeneric
01/2007
1polymyxin B nonapeptideIBA
01/2007
1TabletsIBA
02/2006
1AntacidsIBA
02/2006
1Ranitidine (Zantac)FDA LinkGeneric
05/2005
1Proton Pump InhibitorsIBA
05/2005
1Metronidazole (Metric)FDA LinkGeneric
02/2004
14-(2-oxapentadeca-4-yne)phenylpropanoic acidIBA
02/2004
1Clarithromycin (Biaxin)FDA LinkGeneric
02/2004
1ProstaglandinsIBA
08/2003
1isopropyl unoprostone (Rescula)FDA Link
08/2003
1Antiglaucoma AgentsIBA
08/2003
1Cefotaxime (Kendrick)FDA LinkGeneric
11/2001
1Ampicillin (Omnipen)FDA LinkGeneric
11/2001
1SecretagoguesIBA
01/2001
1Pentagastrin (Peptavlon)FDA Link
01/2001
1Proteins (Proteins, Gene)FDA Link
07/2000
1Atrial Natriuretic Factor (ANF)IBA
07/2000
1Transforming Growth Factor beta1 (TGF beta 1)IBA
03/2000
1Transforming Growth Factor beta (TGF-beta)IBA
03/2000
1Urea (Carbamide)FDA LinkGeneric
02/2000

Therapy/Procedure

10Therapeutics
08/2012 - 06/2000
2Immunotherapy
08/2012 - 06/2008
1Liver Transplantation
04/2015
1Drug Therapy (Chemotherapy)
05/2012
1Ligation
02/2010
1Aftercare (After-Treatment)
11/2004
1Laser Therapy (Surgery, Laser)
08/2003
1Trabeculectomy (Trabeculoplasty)
08/2003
1Lasers (Laser)
08/2003
1Maze Procedure
01/2001